

While trying to stop Sector 21 escapee Hive from turning the world into mindless zombies, Aaron Stone unknowingly transports African Zombie Weevil bugs containing Hive's mind controlling venom back to Eastland. The weevils hitch a ride on S.T.A.N. and end up infecting Jason and half of the school. With the toxic venom slowly transforming them into insects, Aaron must get a sample of Hive's venom to Emma so she can engineer an antidote before it's too late.
A new threat arises when the evil hooded villain, Damaged, frees himself and a bus full of failed experiments, criminals and mutants. Once free, Damaged begins picking off the remaining Omega Defiance members looking for the last vial of intelligence serum. Dr. Necros comes looking to Aaron Stone for protection, but instead lures him into Damaged’s clutches. Meanwhile, Jason is determined to get Charlie a dream job working at the video game and comic store.
When Charlie (Aaron Stone) discovers that his father worked for the Omega Defiance, the news sends him into a tailspin as he tries to prove that his father wasn’t evil. Charlie follows clues left by his father to track down an intelligence serum, which leads Aaron to a rematch with Damaged over the vial. With new threats to the world, T. Abner Hall enlists Vas and Ram to create a "Hero Rising" expansion pack incorporating the new villains to help Charlie train for his inevitable confrontation with this new evil. Meanwhile, Jason pretends to be Charlie as he begins working at the video game and comic store.