The guys visit a historic mansion in Trinway, Ohio, hoping to discover whether an evil entity and other unsettled spirits that allegedly date back to the Civil War still reside on the property.

The Delta Queen, a historic riverboat, was relocated to Houma, LA for extensive renovations, setting off paranormal activity. The Ghost Brothers' mission is to find out what spirit is behind the frightening phenomena.

The Magnolia Hotel in Seguin, Texas, is investigated by the guys, who are on a mission to find out if murders and suicides that have occurred there are linked to an alleged continued presence of threatening paranormal activity.

The Ghost Brothers head to Washington, Georgia to try to solve the mysterious hauntings of The Fitzpatrick Hotel, which was built on a gravesite. Some believe that reports of multiple female spirits residing at the hotel are tied to a tragic death.