New York, NY, 1963. When two young women - just out of college, starting their first jobs in The Big City - wind up dead in their Upper East Side apartment, raped, mutilated, the victims of a terrible, heinous attack, the City is thrown into chaos. If these girls aren't safe, who is? The NYPD is under such pressure to solve the high-profile case it makes a tragic mis-step in the investigation of the case the newspapers dub "The Career Girls Murders."

West Palm Beach, FL, 1955. Judge Curtis Chillingworth (58) and his wife (50's) say their goodbyes to friends at swank dinner party, step into their car and drive away. They are never seen again. When police start investigating they unravel a tale of corruption, moonshine and numbers-running that leaves Florida in shock.

Denver, CO, 1955. When United Airlines Flight 629 bound for Seattle explodes in mid-air, killing everyone aboard, the new-to-air travel nation grieves over the terrible tragedy. But when crash investigators find a few strange inconsistencies in the wreckage they start to wonder if it was an accident at all. What follows is the discovery of the first-ever act of commercial airline sabotage in the United States...the motive? Money.

Michigan, 1967. A young co-ed from Eastern Michigan State University goes missing. Her body is found months later, rotting in a field. A year later, another co-ed, disappears and is found stabbed to death. A few months after that, a young law student is found shot and strangled in an Ypsilanti cemetery. The young women of Southeastern Michigan are terrified and the police commence a massive hunt for the monster they call The Co-Ed Killer.

A 1955 shooting involving a pair of New York socialites is recalled.