Nitya Vasu joins the surgical residency at EMC, driven by vengeance against Dr. Ishan Ahuja, who she blames for maiming her brother, Dr. Dhaval Vasu. But soon, she discovers hidden truths about him.
The story delves into Nitya's life and her fellow residents, set against a poor father's desperate wait for a heart transplant. Meanwhile, Nahida Jaafri struggles with residency stress, relying on pills.