Officers discover firearms that may be intended for a Mexican drug lord; a load of Fentanyl hidden in an ice cream freezer; a truck driver transporting puppies is under scrutiny; a wanted woman is detained in Brownsville.

In their battle against the cartels, Customs and Border Protection flag a tractor-trailer transporting tanks of liquid methamphetamine; officers nab an exotic reptile smuggler; 36 pounds of cocaine are found inside a pickup truck.

Officers question a man traveling with two children that aren't his; a traveler is caught smuggling cash; drugs are found concealed in a flatbed truck; a drunken man is restrained in Progreso, Mexico.

Officers in Laredo, Texas, help a troubled 14-year-old; drugs sent through the mail are seized; a nurse in Progreso, Mexico, is caught smuggling fentanyl; a woman with children is stopped; a drunken woman bares all to officers.

Multiple drug busts and arrests get made at various border crossings in Texas, including the discovery of the largest meth haul yet attempted at the Pharr-Reynosa International Bridge.

At the Brownsville, Texas, point of entry, officers encounter drug trafficking, fraudulent documents and illegal merchandise; authorities seize $7 million worth of marijuana hidden inside a rolled carpet during a routine cargo inspection.

Meth is found inside the walls of a trailer; brothers are caught smuggling prescription medication; illicit Mexican delicacies are confiscated at the border.

Upon detaining a woman smuggling Tramadol and Xanax pills, officers discover she is part of a larger drug ring; officers arrest a daily crosser after finding cocaine in her vehicle; an officer's hunch leads to the discovery of 500 kilos of marijuana.

Officers discover methamphetamine hidden inside a truck's speakers and confiscate drugs packed deep within lead boxes; a woman denies trafficking pain pills; a man is interviewed to confirm his citizenship.