Heather asks for a off for Earth Day, Syd treats a mom to be but gives up a trip to New York but needs to help a mom to be have her baby and hope the dad will donate blood to help save the baby's life. Doug gets a new job in Ohio and asks Joanie to go with him. Syd is unable to go to New York for a reunion and the person she hasn't seen in 10 years drops by.
In this season's opener, an out-of-control Mercedes smashes through a wall of the clinic; Molly, a mentally disturbed and dellusional young woman, holds Syd (Melina Kanakaredes) at gunpoint because she thinks she kidnapped her baby; and Helen contemplates a new career, away from the clinic. Meanwhile, Joanie hires Doug Dog Boy Boyce to help her out at the Barkery.