Farma accompanies his father Bruno on his house call to the Empress. He realizes he has the ability to cure her, but he can't do so without drawing attention that would put him in jeopardy.

Farma continues to treat Empress Élisabeth II, which leads to an unexpected reward.

Farma's efforts to create a pharmacy for everyone, nobles and commoners alike, aren't achieving the desired results. But with some help and advice from family and friends, Farma might be able to turn things around.

The de Médicis family visits Bruno's newly granted territory of Marseirre so Bruno can be briefed on the situation there. The seaside location provides the perfect opportunity for a beach trip. Upon returning from Marseirre, Farma finds that his pharmacy is even busier than before. However, with this higher profile comes unwanted attention.

Farma confronts Grand Temple Inquisitor Salomon, and his sudden conflict with the Inquisition takes a surprising turn.

Demand for Parallel World Pharmacy's products continues to rise, exceeding the store's capacity to handle. Everyone would benefit if other shops sold Farma's new medicines, but the Saint Fleuve Pharmaceutist Guild strictly forbids its members from involvement with Farma's shop or his medicines. Farma searches for a way to expand access to medicine in this environment.

Things are looking up in the Saint Fleuve Empire, with Farma's initiatives improving the overall health of the populace. However, word arrives of a mysterious new illness that threatens to sweep the nation. Farma rushes to prepare for this frightening scenario.

With the Saint Fleuve Fair about to begin, Farma fights to keep the Black Death from ravaging the Empire.

As Farma works to save the villagers of L'Estacque, the infected cargo and crew from the rogue ship get ever closer to the capital.

Farma reaches the capital only to find that plague is spreading swiftly through the city. Can he and the people of the capital get the situation under control and defeat this epidemic?